Statins and PCSK9 Inhibitors Tied to Higher Microvascular Risk in Diabetes
This Mendelian randomization (MR) study investigated whether three classes of cholesterol-lowering drugs—HMGCR inhibitors (eg, statins), PCSK9 inhibitors, and NPC1L1 inhibitors—causally affect the risk of diabetic microvascular complications.
Impact of GLP-1 Receptor Agonists on Immune Function and Vaccine Response
Glucagon-like peptide-1 receptor agonists (GLP-1RAs), like semaglutide, are widely used for managing diabetes and weight loss. However, their extended use raises concerns about their impact on immune responses, particularly vaccine efficacy. Unlike natural GLP-1, GLP-1RAs have longer half-lives and are administered at higher concentrations, potentially affecting immune cells beyond the pancreas.
Iron Deficiency Linked to Higher Diabetic Kidney Disease Risk, but Iron Supplements Remain Safe
Researchers of a recent study explored the relationship between iron deficiency anemia (IDA) and diabetic kidney disease (DKD) in patients with type 2 diabetes mellitus.
Black Tea With Inulin and Dextrin Reduces Post-Meal Glucose Spikes in T2DM
In this randomized, double-blind, placebo-controlled crossover trial, researchers evaluated the effect of black tea drinks with inulin and dextrin (BTID) on postprandial glucose levels in individuals with type 2 diabetes mellitus (T2DM).
Spinal Cord Stimulation: A Promising Solution for Pain Relief in Diabetic Peripheral Neuropathy
Spinal cord stimulation (SCS) has emerged as an effective treatment for managing pain from diabetic peripheral neuropathy (DPN), especially when other therapies are ineffective.
Low-Carb Mediterranean and Plant-Based Diets Show Promise for T2D Remission
A recent evaluated the effectiveness of food-based dietary approaches in achieving remission for individuals with type 2 diabetes (T2D). A systematic search of Medline, EMBASE, and Web of Science was conducted to identify longitudinal studies, which were then assessed for quality.
FIND Trial: No Link Between Vitamin D3 and Type 2 Diabetes Risk in Older Adults
The Finnish Vitamin D Trial (FIND) aimed to evaluate the impact of vitamin D3 supplementation on the incidence of type 2 diabetes in healthy older adults.
Managing Type 2 Diabetes: Personalized Dietary Strategies for Long-Term Outcomes and Quality of Life
Type 2 diabetes mellitus (T2DM) is a chronic, highly prevalent disease linked to aging, sedentary lifestyles, and poor dietary habits, particularly obesity. Obesity contributes significantly to T2DM and other conditions like hypertension and cardiovascular disease.
Umbrella Review Finds CGM Improves Glycemic Control in T2D, but Patient Outcomes Inconclusive
A recent umbrella review evaluated the effectiveness of continuous glucose monitoring (CGM) in patients with type 2 diabetes (T2D) compared to self-monitoring blood glucose or usual care.
